San Diego, California, United States

🇺🇸 San Diego is a city in the U.S. state of California on the coast of the Pacific Ocean and immediately adjacent to the Mexican border. San Diego is the eighth most populous city in the United States and second most populous in California. The city is the county seat of San Diego County. The city is known for its mild year-round climate, natural deep-water harbour, extensive beaches and parks, long association with the United States Navy and Marine Corps, and recent emergence as a healthcare and biotechnology development centre.

Historically home to the Kumeyaay people, San Diego is frequently referred to as the "Birthplace of California", as it was the first site visited and settled by Europeans on what is now the West Coast of the United States. Upon landing in San Diego Bay in 1542, Juan Rodríguez Cabrillo claimed the area for Spain, forming the basis for the settlement of Alta California 200 years later. The Presidio and Mission San Diego de Alcalá, founded in 1769, formed the first European settlement in what is now California. In 1821, San Diego became part of the newly declared Mexican Empire, which reformed as the First Mexican Republic two years later. California was conquered by the U.S. in 1848 following the Mexican–American War and was admitted to the union as a state in 1850.

San Diego's main economic engines are military and defence related activities, tourism, international trade, research, and manufacturing. The city is the economic centre of the San Diego–Tijuana conurbation. The primary border crossing between San Diego and Tijuana, the San Ysidro Port of Entry, is the busiest international land border crossing in the world outside of Asia. The city's primary airport, San Diego International Airport, is the busiest single-runway airport in the world.

History: Pre-colonial What has been referred to as the San Dieguito complex was established in the area at least 9,000 years ago. The Kumeyaay may have culturally evolved from this complex or migrated into the area around 1000 C.E. Archaeologist Malcolm Rogers hypothesized that the early cultures of San Diego were separate from the Kumeyaay, yet this claim is disputed, with others noting that it does not account for cultural evolution. Rogers later reevaluated his claims, yet they were influential in shaping historical tellings of early San Diego history.

The Kumeyaay established villages scattered across the region, including the village of Kosa'aay which was the Kumeyaay village that the future settlement of San Diego would stem from in today's Old Town. The village of Kosa'aay was made up of thirty to forty families living in pyramid-shaped housing structures and was supported by a freshwater spring from the hillsides.

Spanish period The first European to visit the region was explorer Juan Rodríguez Cabrillo, sailing under the flag of Castile but possibly born in Portugal. Sailing his flagship San Salvador from Navidad, New Spain, Cabrillo claimed the bay for the Spanish Empire in 1542, and named the site "San Miguel". In November 1602, Sebastián Vizcaíno was sent to map the California coast. Arriving on his flagship San Diego, Vizcaíno surveyed the harbor and what are now Mission Bay and Point Loma and named the area for the Catholic Saint Didacus, a Spaniard more commonly known as San Diego de Alcalá. On November 12, 1602, the first Christian religious service of record in Alta California was conducted by Friar Antonio de la Ascensión, a member of Vizcaíno's expedition, to celebrate the feast day of San Diego.

The permanent European colonization of both California and San Diego began in 1769 with the arrival of four contingents of Spaniards from New Spain and the Baja California peninsula. Two seaborne parties reached San Diego Bay: the San Carlos, under Vicente Vila and including as notable members the engineer and cartographer Miguel Costansó and the soldier and future governor Pedro Fages, and the San Antonio, under Juan Pérez. An initial overland expedition to San Diego from the south was led by the soldier Fernando Rivera and included the Franciscan missionary, explorer, and chronicler Juan Crespí, followed by a second party led by the designated governor Gaspar de Portolà and including the mission president (and now saint) Junípero Serra.

In May 1769, Portolà established the Fort Presidio of San Diego on a hill near the San Diego River above the Kumeyaay village of Cosoy, which would later become incorporated into the Spanish settlement, making it the first settlement by Europeans in what is now the state of California. In July of the same year, Mission San Diego de Alcalá was founded by Franciscan friars under Serra. The mission became a site for a Kumeyaay revolt in 1775, which forced the mission to relocate six miles (10 km) up the San Diego River. By 1797, the mission boasted the largest native population in Alta California, with over 1,400 neophytes living in and around the mission proper. Mission San Diego was the southern anchor in Alta California of the historic mission trail El Camino Real. Both the Presidio and the Mission are National Historic Landmarks.

Mexican period In 1821, Mexico won its independence from Spain, and San Diego became part of the Mexican territory of Alta California. In 1822, Mexico began its attempt to extend its authority over the coastal territory of Alta California. The fort on Presidio Hill was gradually abandoned, while the town of San Diego grew up on the level land below Presidio Hill. The Mission was secularized by the Mexican government in 1834, and most of the Mission lands were granted to former soldiers. The 432 residents of the town petitioned the governor to form a pueblo, and Juan María Osuna was elected the first alcalde ("municipal magistrate"), defeating Pío Pico in the vote. Beyond the town, Mexican land grants expanded the number of California ranchos that modestly added to the local economy.

However, San Diego had been losing population throughout the 1830s, due to increasing tension between the settlers and the indigenous Kumeyaay and in 1838 the town lost its pueblo status because its size dropped to an estimated 100 to 150 residents. The ranchos in the San Diego region would face Kumeyaay raids in the late 1830s and the town itself would face raids in the 1840s.

Americans gained an increased awareness of California, and its commercial possibilities, from the writings of two countrymen involved in the often officially forbidden, to foreigners, but economically significant hide and tallow trade, where San Diego was a major port and the only one with an adequate harbor: William Shaler's "Journal of a Voyage Between China and the North-Western Coast of America, Made in 1804" and Richard Henry Dana's more substantial and convincing account, of his 1834–36 voyage, the classic Two Years Before the Mast.

In 1846, the United States went to war against Mexico and sent a naval and land expedition to conquer Alta California. At first, they had an easy time of it, capturing the major ports including San Diego, but the Californios in southern Alta California struck back. Following the successful revolt in Los Angeles, the American garrison at San Diego was driven out without firing a shot in early October 1846. Mexican partisans held San Diego for three weeks until October 24, 1846, when the Americans recaptured it. For the next several months the Americans were blockaded inside the pueblo. Skirmishes occurred daily and snipers shot into the town every night. The Californios drove cattle away from the pueblo hoping to starve the Americans and their Californio supporters out. On December 1, the American garrison learned that the dragoons of General Stephen W. Kearney were at Warner's Ranch. Commodore Robert F. Stockton sent a mounted force of fifty under Captain Archibald Gillespie to march north to meet him. Their joint command of 150 men, returning to San Diego, encountered about 93 Californios under Andrés Pico.

In the ensuing Battle of San Pasqual, fought in the San Pasqual Valley which is now part of the city of San Diego, the Americans suffered their worst losses in the campaign. Subsequently, a column led by Lieutenant Gray arrived from San Diego, rescuing Kearny's battered and blockaded command. Stockton and Kearny went on to recover Los Angeles and force the capitulation of Alta California with the "Treaty of Cahuenga" on January 13, 1847. As a result of the Mexican–American War of 1846–48, the territory of Alta California, including San Diego, was ceded to the United States by Mexico, under the terms of the Treaty of Guadalupe Hidalgo in 1848. The Mexican negotiators of that treaty tried to retain San Diego as part of Mexico, but the Americans insisted that San Diego was "for every commercial purpose of nearly equal importance to us with that of San Francisco", and the Mexican–American border was eventually established to be one league south of the southernmost point of San Diego Bay, so as to include the entire bay within the United States.

American period The state of California was admitted to the United States in 1850. That same year San Diego was designated the seat of the newly established County of San Diego and was incorporated as a city. Joshua H. Bean, the last alcalde of San Diego, was elected the first mayor. Two years later the city was bankrupt; the California legislature revoked the city's charter and placed it under control of a board of trustees, where it remained until 1889. A city charter was reestablished in 1889, and today's city charter was adopted in 1931.

The original town of San Diego was located at the foot of Presidio Hill, in the area which is now Old Town San Diego State Historic Park. The location was not ideal, being several miles away from navigable water at its port at La Playa. In 1850, William Heath Davis promoted a new development by the bay shore called "New San Diego", several miles south of the original settlement; however, for several decades the new development consisted only of a pier, a few houses and an Army depot for the support of Fort Yuma. After 1854, the fort became supplied by sea and by steamboats on the Colorado River and the depot fell into disuse. From 1857 to 1860, San Diego became the western terminus of the San Antonio-San Diego Mail Line, the earliest overland stagecoach and mail operation from the Eastern United States to California, coming from Texas through New Mexico Territory in less than 30 days.

In the late 1860s, Alonzo Horton promoted a move to the bayside area, which he called "New Town" and which became Downtown San Diego. Horton promoted the area heavily, and people and businesses began to relocate to New Town because its location on San Diego Bay was convenient to shipping. New Town soon eclipsed the original settlement, known to this day as Old Town, and became the economic and governmental heart of the city. Still, San Diego remained a relative backwater town until the arrival of a railroad connection in 1878. In 1884–1886, John J. Montgomery made the first controlled flights by an American in a heavier-than-air unpowered glider just south of San Diego at Otay Mesa, helping to pioneer a new science of aerodynamics.

In 1912, San Diego was the site of a free speech fight between the Industrial Workers of the World and the city government who passed an ordinance forbidding the freedom of speech along an area of "Soapbox Row" that led to civil disobedience, vigilantism, police violence, the abduction of Emma Goldman's husband Ben Reitman and multiple riots. San Diego's proximity to Tijuana during the Mexican Revolution made this one of the most significant free speech fights during the Wobbly era.

In 1916, the neighborhood of Stingaree, the original home of San Diego's first Chinatown and "Soapbox Row", was demolished by anti-vice campaigners to make way for the Gaslamp Quarter.

In the early part of the 20th century, San Diego hosted the World's Fair twice: the Panama-California Exposition (1915) and the California Pacific International Exposition in 1935. Both expositions were held in Balboa Park, and many of the Spanish/Baroque-style buildings that were built for those expositions remain to this day as central features of the park. The buildings were intended to be temporary structures, but most remained in continuous use until they progressively fell into disrepair. Most were eventually rebuilt, using castings of the original façades to retain the architectural style. The menagerie of exotic animals featured at the 1915 exposition provided the basis for the San Diego Zoo. During the 1950s there was a citywide festival called Fiesta del Pacifico highlighting the area's Spanish and Mexican past. In the 2010s there was a proposal for a large-scale celebration of the 100th anniversary of Balboa Park, but the plans were abandoned when the organization tasked with putting on the celebration went out of business.

The southern portion of the Point Loma peninsula was set aside for military purposes as early as 1852. Over the next several decades the Army set up a series of coastal artillery batteries and named the area Fort Rosecrans. Significant U.S. Navy presence began in 1901 with the establishment of the Navy Coaling Station in Point Loma, and expanded greatly during the 1920s. By 1930, the city was host to Naval Base San Diego, Naval Training Center San Diego, San Diego Naval Hospital, Camp Matthews, and Camp Kearny (now Marine Corps Air Station Miramar). The city was also an early centre for aviation: as early as World War I, San Diego was proclaiming itself "The Air Capital of the West". The city was home to important airplane developers and manufacturers like Ryan Airlines (later Ryan Aeronautical), founded in 1925, and Consolidated Aircraft (later Convair), founded in 1923. Charles A. Lindbergh's plane The Spirit of St. Louis was built in San Diego in 1927 by Ryan Airlines.

During World War II, San Diego became a major hub of military and defense activity, due to the presence of so many military installations and defense manufacturers. The city's population grew rapidly during and after World War II, more than doubling between 1930 (147,995) and 1950 (333,865). During the final months of the war, the Japanese had a plan to target multiple U.S. cities for biological attack, starting with San Diego. The plan was called "Operation Cherry Blossoms at Night" and called for kamikaze planes filled with fleas infected with plague (Yersinia pestis) to crash into civilian population centres in the city, hoping to spread plague in the city and effectively kill tens of thousands of civilians. The plan was scheduled to launch on September 22, 1945, but was not carried out because Japan surrendered five weeks earlier.

After World War II, the military continued to play a major role in the local economy, but post-Cold War cutbacks took a heavy toll on the local defense and aerospace industries. The resulting downturn led San Diego leaders to seek to diversify the city's economy by focusing on research and science, as well as tourism.

From the start of the 20th century through the 1970s, the American tuna fishing fleet and tuna canning industry were based in San Diego, "the tuna capital of the world". San Diego's first tuna cannery was founded in 1911, and by the mid-1930s the canneries employed more than 1,000 people. A large fishing fleet supported the canneries, mostly staffed by immigrant fishermen from Japan, and later from the Portuguese Azores and Italy whose influence is still felt in neighborhoods like Little Italy and Point Loma. Due to rising costs and foreign competition, the last of the canneries closed in the early 1980s.

Downtown San Diego was in decline in the 1960s and 1970s, but experienced some urban renewal since the early 1980s, including the opening of Horton Plaza, the revival of the Gaslamp Quarter, and the construction of the San Diego Convention Center; Petco Park opened in 2004. Outside of downtown, San Diego annexed large swaths of land and for suburban expansion to the north and control of the San Ysidro Port of Entry.

As the Cold War ended, the military shrank and so did defense spending. San Diego has since become a centre of the emerging biotech industry and is home to telecommunications giant Qualcomm. San Diego had also grown in the tourism industry with the popularity of attractions such as the San Diego Zoo, SeaWorld San Diego, and Legoland California in Carlsbad.

Geography According to SDSU professor emeritus Monte Marshall, San Diego Bay is "the surface expression of a north-south-trending, nested graben". The Rose Canyon and Point Loma fault zones are part of the San Andreas Fault system. About 40 miles (64 km) east of the bay are the Laguna Mountains in the Peninsular Ranges, which are part of the backbone of the American continents.

The city lies on approximately 200 deep canyons and hills separating its mesas, creating small pockets of natural open space scattered throughout the city and giving it a hilly geography. Traditionally, San Diegans have built their homes and businesses on the mesas, while leaving the urban canyons relatively wild. Thus, the canyons give parts of the city a segmented feel, creating gaps between otherwise proximate neighborhoods and contributing to a low-density, car-centered environment. The San Diego River runs through the middle of San Diego from east to west, creating a river valley that serves to divide the city into northern and southern segments. During the historic period and presumably earlier as well, the river has shifted its flow back and forth between San Diego Bay and Mission Bay, and its fresh water was the focus of the earliest Spanish explorers. Miguel Costansó, a cartographer, wrote in 1769, "When asked by signs where the watering-place was, the Indians pointed to a grove which could be seen at a considerable distance to the north-east, giving to understand that a river or creek flowed through it, and that they would lead our men to it if they would follow". That river was the San Diego River. Several reservoirs and Mission Trails Regional Park also lie between and separate developed areas of the city.

Notable peaks within the city limits include Cowles Mountain, the highest point in the city at 1,591 feet (485 m); Black Mountain at 1,558 feet (475 m); and Mount Soledad at 824 feet (251 m). The Cuyamaca Mountains and Laguna Mountains rise to the east of the city, and beyond the mountains are desert areas. The Cleveland National Forest is a half-hour drive from downtown San Diego. Numerous farms are found in the valleys north-east and south-east of the city.

In its 2013 ParkScore ranking, The Trust for Public Land reported that San Diego had the 9th-best park system among the 50 most populous U.S. cities. ParkScore ranks city park systems by a formula that analyzes acreage, access, and service and investment.

Ecology Like much of Southern California, the majority of San Diego's current area was originally occupied on the west by coastal sage scrub and on the east by chaparral, plant communities made up mostly of drought-resistant shrubs. The steep and varied topography and proximity to the ocean create a number of different habitats within the city limits, including tidal marsh and canyons. The chaparral and coastal sage scrub habitats in low elevations along the coast are prone to wildfire, and the rates of fire increased in the 20th century, due primarily to fires starting near the borders of urban and wild areas.

San Diego's broad city limits encompass a number of large nature preserves, including Torrey Pines State Reserve, Los Peñasquitos Canyon Preserve, and Mission Trails Regional Park. Torrey Pines State Reserve and a coastal strip continuing to the north constitute one of only two locations where the rare species of Torrey Pine, Pinus torreyana, is found. Due to the steep topography that prevents or discourages building, along with some efforts for preservation, there are also a large number of canyons within the city limits that serve as nature preserves, including Switzer Canyon, Tecolote Canyon Natural Park, and Marian Bear Memorial Park in San Clemente Canyon, as well as a number of small parks and preserves.

San Diego County has one of the highest counts of animal and plant species that appear on the endangered list of counties in the United States. Because of its diversity of habitat and its position on the Pacific Flyway, San Diego County has recorded 492 different bird species, more than any other region in the country. San Diego always scores high in the number of bird species observed in the annual Christmas Bird Count, sponsored by the Audubon Society, and it is known as one of the "birdiest" areas in the United States.

San Diego and its backcountry suffer from periodic wildfires. In October 2003, San Diego was the site of the Cedar Fire, at that time the largest wildfire in California over the past century. The fire burned 280,000 acres (1,100 km²), killed 15 people, and destroyed more than 2,200 homes. In addition to damage caused by the fire, smoke resulted in a significant increase in emergency room visits due to asthma, respiratory problems, eye irritation, and smoke inhalation; the poor air quality caused San Diego County schools to close for a week. Wildfires four years later destroyed some areas, particularly within Rancho Bernardo, as well as the nearby communities of Rancho Santa Fe and Ramona.

Neighborhoods The City of San Diego recognizes 52 individual areas as Community Planning Areas. Within a given planning area there may be several distinct neighborhoods. Altogether the city contains more than 100 identified neighborhoods.

Downtown San Diego is located on San Diego Bay. Balboa Park encompasses several mesas and canyons to the north-east, surrounded by older, dense urban communities including Hillcrest and North Park. To the east and south-east lie City Heights, the College Area, and Southeast San Diego. To the north lies Mission Valley and Interstate 8. The communities north of the valley and freeway, and south of Marine Corps Air Station Miramar, include Clairemont, Kearny Mesa, Tierrasanta, and Navajo. Stretching north from Miramar are the northern suburbs of Mira Mesa, Scripps Ranch, Rancho Peñasquitos, and Rancho Bernardo. The far north-east portion of the city encompasses Lake Hodges and the San Pasqual Valley, which holds an agricultural preserve. Carmel Valley and Del Mar Heights occupy the north-west corner of the city. To their south are Torrey Pines State Reserve and the business centre of the Golden Triangle. Further south are the beach and coastal communities of La Jolla, Pacific Beach, Mission Beach, and Ocean Beach. Point Loma occupies the peninsula across San Diego Bay from downtown. The communities of South San Diego (an Exclave), such as San Ysidro and Otay Mesa, are located next to the Mexico–United States border, and are physically separated from the rest of the city by the cities of National City and Chula Vista. A narrow strip of land at the bottom of San Diego Bay connects these southern neighborhoods with the rest of the city.

For the most part, San Diego neighborhood boundaries tend to be understood by its residents based on geographical boundaries like canyons and street patterns. The city recognised the importance of its neighborhoods when it organized its 2008 General Plan around the concept of a "City of Villages".

Cityscape San Diego was originally centered on the Old Town district, but by the late 1860s the focus had shifted to the bayfront, in the belief that this new location would increase trade. As the "New Town" – present-day Downtown – waterfront location quickly developed, it eclipsed Old Town as the centre of San Diego.

The development of skyscrapers over 300 feet (91 m) in San Diego is attributed to the construction of the El Cortez Hotel in 1927, the tallest building in the city from 1927 to 1963. As time went on, multiple buildings claimed the title of San Diego's tallest skyscraper, including the Union Bank of California Building and Symphony Towers. Currently the tallest building in San Diego is One America Plaza, standing 500 feet (150 m) tall, which was completed in 1991. The downtown skyline contains no super-talls, as a regulation put in place by the Federal Aviation Administration in the 1970s set a 500 feet (152 m) limit on the height of buildings within a one-mile (1.6 km) radius of the San Diego International Airport. An iconic description of the skyline includes its skyscrapers being compared to the tools of a toolbox.

There are several new high-rises under construction, including two that exceed 400 feet (122 m) in height.

Economy The largest sectors of San Diego's economy are defense/military, tourism, international trade, and research/manufacturing. In 2014, San Diego was designated by a Forbes columnist as the best city in the country to launch a small business or startup company. San Diego recorded a median household income of $79,646 in 2018, an increase of 3.89% from $76,662 in 2017. The median property value in San Diego in 2018 was $654,700, and the average home has two cars per household.

Economy: Top employers According to the city's 2022 Annual Comprehensive Financial Report, the top employers in the city include: Naval Base San Diego; University of California, San Diego; Sharp Health Care; County of San Diego; Scripps Health; San Diego Unified School District; Qualcomm, Inc.; City of San Diego; Kaiser Permanente; Northrop Grumman Corporation.

Defense and military The economy of San Diego is influenced by its deep water port, which includes the only major submarine and shipbuilding yards on the West Coast. Several major national defense contractors were started and are headquartered in San Diego, including General Atomics, Cubic, and NASSCO.

San Diego hosts the largest naval fleet in the world: In 2008 it was home to 53 ships, over 120 tenant commands, and more than 35,000 sailors, marines, Department of Defense civilian employees and contractors. About 5 percent of all civilian jobs in the county are military-related, and 15,000 businesses in San Diego County rely on Department of Defense contracts.

Marine Corps Recruit Depot

Military bases in San Diego include US Navy facilities, Marine Corps bases, and Coast Guard stations. The city is "home to the majority of the U.S. Pacific Fleet's surface combatants, all of the Navy's West Coast amphibious ships and a variety of Coast Guard and Military Sealift Command vessels".

The military infrastructure in San Diego is still growing and developing, with numerous military personnel stationed there, numbers of which are expected to rise. This plays a significant role in the city's economy, as of 2020, it provides roughly 25% of the GDP and provides 23% of the total jobs in San Diego.

Tourist Industry Tourism is a major industry owing to the city's climate, beaches, and tourist attractions such as Balboa Park, Belmont amusement park, San Diego Zoo, San Diego Zoo Safari Park, and SeaWorld San Diego. San Diego's Spanish and Mexican heritage is reflected in many historic sites across the city, such as Mission San Diego de Alcalá and Old Town San Diego State Historic Park. Also, the local craft brewing industry attracts an increasing number of visitors for "beer tours" and the annual San Diego Beer Week in November; San Diego has been called "America's Craft Beer Capital".

San Diego County hosted more than 32 million visitors in 2012; collectively they spent an estimated $8 billion. The visitor industry provides employment for more than 160,000 people.

San Diego's cruise ship industry used to be the second-largest in California. Numerous cruise lines operate out of San Diego. However, cruise ship business has been in decline since 2008, when the Port hosted over 250 ship calls and more than 900,000 passengers. By 2016–2017, the number of ship calls had fallen to 90.

Local sightseeing cruises are offered in San Diego Bay and Mission Bay, as well as whale-watching cruises to observe the migration of gray whales, peaking in mid-January. Sport fishing is another popular tourist attraction; San Diego is home to southern California's biggest sport fishing fleet.

International trade San Diego's commercial port and its location on the United States–Mexico border make international trade an important factor in the city's economy. The city is authorized by the United States government to operate as a Foreign Trade Zone.

The city shares a 15-mile (24 km) border with Mexico that includes two border crossings. San Diego hosts the busiest international border crossing in the world, in the San Ysidro neighborhood at the San Ysidro Port of Entry. A second, primarily commercial border crossing operates in the Otay Mesa area; it is the largest commercial crossing on the California–Baja California border and handles the third-highest volume of trucks and dollar value of trade among all United States-Mexico land crossings.

The Port of San Diego is the third-busiest port in California and one of the busiest on the West Coast. One of the Port of San Diego's two cargo facilities is located in Downtown San Diego at the Tenth Avenue Marine Terminal. This terminal has facilities for containers, bulk cargo, and refrigerated and frozen storage, so that it can handle the import and export of many commodities. In 2009 the Port of San Diego handled 1,137,054 short tons of total trade; foreign trade accounted for 956,637 short tons while domestic trade amounted to 180,417 short tons.

Historically tuna fishing and canning was one of San Diego's major industries, although the American tuna fishing fleet is no longer based in San Diego. Seafood company Bumble Bee Foods is headquartered in San Diego, as was Chicken of the Sea until 2018.

Companies San Diego hosts several major producers of wireless cellular technology. Qualcomm was founded and is headquartered in San Diego, and is one of the largest private-sector employers in San Diego. Other wireless industry manufacturers headquartered here include Nokia, LG Electronics, Kyocera International, Cricket Communications and Novatel Wireless. San Diego also has the U.S. headquarters for the Slovakian security company ESET. San Diego has been designated as an iHub Innovation Center for potential collaboration between wireless and the life sciences.

The University of California, San Diego and other research institutions have helped to fuel the growth of biotechnology. In 2013, San Diego had the second-largest biotech cluster in the United States, below the Boston area and above the San Francisco Bay Area. There are more than 400 biotechnology companies in the area. In particular, the La Jolla and nearby Sorrento Valley areas are home to offices and research facilities for numerous biotechnology companies. Major biotechnology companies like Illumina and Neurocrine Biosciences are headquartered in San Diego, while many other biotech and pharmaceutical companies have offices or research facilities in San Diego. San Diego is also home to more than 140 contract research organizations (CROs) that provide contract services for pharmaceutical and biotechnology companies.

Real estate San Diego has high real estate prices. San Diego home prices peaked in 2005, and then declined along with the national trend. As of December 2010, prices were down 36 percent from the peak, median price of homes having declined by more than $200,000 between 2005 and 2010. As of May 2015, the median price of a house was $520,000. In November 2018 the median home price was $558,000. The San Diego metropolitan area had one of the worst housing affordability rankings of all metropolitan areas in the United States in 2009. The San Diego Housing Market experienced a decline in the median sold price of existing single-family homes between December 2022 and January 2023, with a 2.9% decrease from $850,000 to $824,950.

Consequently, San Diego has experienced negative net migration since 2004. A significant number of people have moved to adjacent Riverside County, commuting daily to jobs in San Diego, while others are leaving the area altogether and moving to more affordable regions.

Education: Universities According to education rankings released by the U.S. Census Bureau in 2017, 44.4% of San Diegans (city, not county) ages 25 and older hold bachelor's degrees, compared to 30.9% in the United States as a whole. The census ranks the city as the ninth-most educated city in the United States, based on these figures.

The largest university in the area is the University of California, San Diego (UC San Diego). The university is the southernmost campus of the University of California system and is the second largest employer in the city. It is the only university in the city that is classified "R1: Doctoral Universities – Very high research activity", and it has the 7th largest research expenditure in the country.

Other public colleges and universities in the city include San Diego State University (SDSU) and the San Diego Community College District, which includes San Diego City College, San Diego Mesa College, and San Diego Miramar College.

Private non-profit colleges and universities in the city include the University of San Diego (USD), Point Loma Nazarene University (PLNU), National University's San Diego campus, University of Redlands' School of Business San Diego campus, Brandman University's San Diego campus, San Diego Christian College, and John Paul the Great Catholic University. For-profit institutions include Alliant International University (AIU), California International Business University (CIBU), California College San Diego, Fashion Institute of Design & Merchandising's San Diego campus, NewSchool of Architecture and Design, Platt College, Southern States University (SSU), UEI College, and Woodbury University School of Architecture's satellite campus.

There is one medical school in the city, the UC San Diego School of Medicine. There are three ABA accredited law schools in the city, which include California Western School of Law, Thomas Jefferson School of Law, and University of San Diego School of Law. There is also one law school, Western Sierra Law School, not accredited by the ABA.

Libraries The city-run San Diego Public Library system is headquartered downtown and has 36 branches throughout the city. The newest location is in Skyline Hills, which broke ground in 2015. The libraries have had reduced operating hours since 2003 due to the city's financial problems. In 2006 the city increased spending on libraries by $2.1 million. A new nine-story Central Library on Park Boulevard at J Street opened on September 30, 2013.

In addition to the municipal public library system, there are nearly two dozen libraries open to the public run by other governmental agencies, and by schools, colleges, and universities. Noteworthy are the Malcolm A. Love Library at San Diego State University, and the Geisel Library at the University of California, San Diego.

Culture The culture of San Diego, California is influenced heavily by the mixing of American and Mexican cultures, due to the city's position on the Mexican-American border, its large Chicano population, and its history as part of Hispanic America and Mexico. San Diego's longtime association with the U.S. military also contributes to its culture.

Many popular museums, such as the San Diego Museum of Art, the San Diego Natural History Museum, the Museum of Us, the Museum of Photographic Arts, and the San Diego Air & Space Museum, are located in Balboa Park, which is also the location of the San Diego Zoo. The Museum of Contemporary Art San Diego (MCASD) is located in La Jolla and has a branch located at the Santa Fe Depot downtown. The downtown branch consists of two buildings on two opposite streets.

The Columbia district downtown is home to historic ship exhibits belonging to the San Diego Maritime Museum, headlined by the Star of India, as well as the unrelated San Diego Aircraft Carrier Museum featuring the USS Midway aircraft carrier.

The San Diego Symphony at Symphony Towers performs on a regular basis; from 2004 to 2017, its director was Jahja Ling. The San Diego Opera at Civic Center Plaza, directed by David Bennett. Old Globe Theatre at Balboa Park produces about 15 plays and musicals annually. The La Jolla Playhouse at UCSD is directed by Christopher Ashley. Both the Old Globe Theatre and the La Jolla Playhouse have produced the world premieres of plays and musicals that have gone on to win Tony Awards or nominations on Broadway. The Joan B. Kroc Theatre at Kroc Center's Performing Arts Center is a 600-seat state-of-the-art theater that hosts music, dance, and theater performances. The San Diego Repertory Theatre at the Lyceum Theatres in Westfield Horton Plaza produces a variety of plays and musicals. Hundreds of movies and a dozen TV shows have been filmed in San Diego, a tradition going back as far as 1898.

Sport San Diego is home to two active major professional sports teams. The San Diego Padres are a Major League Baseball (MLB) franchise that began play in 1969. An expansion team in Major League Soccer was announced in 2023 and will begin play in 2025. The area is also home to several other highest-level professional teams, minor league teams, semi-pro and amateur teams, and college athletics teams.

The region has previously hosted the National Football League (NFL)'s Chargers and the National Basketball Association (NBA)'s Rockets and Clippers, all three of which relocated from the San Diego area (Chargers and Clippers going to the Los Angeles area, and Rockets going to Houston) due to a combination of ownership and stadium/arena issues. San Diego has additionally been the past home of two other defunct major professional teams: the San Diego Conquistadors/Sails, which competed in the American Basketball Association (ABA) for four seasons before folding less than a year prior to the ABA–NBA merger of 1976, and the San Diego Mariners, which played three seasons in the World Hockey Association (WHA) before folding less than two years before the NHL–WHA merger of 1979.

Media Published within the city are the daily newspaper, The San Diego Union Tribune and its online portal of the same name, and the alternative newsweeklies, the San Diego CityBeat and San Diego Reader. Times of San Diego is a free online newspaper covering news in the metropolitan area. Voice of San Diego is a non-profit online news outlet covering government, politics, education, neighborhoods, and the arts. The San Diego Daily Transcript is a business-oriented online newspaper.

San Diego is also the headquarters of national far-right cable TV channel One America News Network (OANN), which was founded in 2013 and is owned by Herring Networks. The network gained notoriety for being ardent supporters of Donald Trump and providing a platform for right-wing conspiracy theories.

San Diego led U.S. local markets with 69.6 percent broadband penetration in 2004 according to Nielsen//NetRatings.

San Diego's first television station was KFMB, which began broadcasting on May 16, 1949. Since the Federal Communications Commission (FCC) licensed seven television stations in Los Angeles, two VHF channels were available for San Diego because of its relative proximity to the larger city. In 1952, however, the FCC began licensing UHF channels, making it possible for cities such as San Diego to acquire more stations. Stations based in Mexico (with ITU prefixes of XE and XH) also serve the San Diego market. Television stations today include XHCPDE 11 (Canal Once (Mexico)), XETV 6 (Canal 5/Nueve), KFMB 8 (CBS, with The CW/MNTV on DT2), KGTV 10 (ABC), XEWT 12 (Televisa Regional), KPBS 15 (PBS), KBNT-CD 17 (Univision), XHTIT-TDT 21 (Azteca 7), XHJK-TDT 1 (Azteca Uno), XHAS 33 (Azteca America), K35DG-D 35 (UCSD-TV), KDTF-LD 36 (Unimás), KNSD 39 (NBC), KUAN-LD 48 (Telemundo), KSEX-CD 42 (Infomercials), XHBJ-TDT 45 (Canal 6 (Mexico)), XHDTV 49 (Milenio Televisión), KUSI 51 (Independent), XHUAA-TDT 19 (Canal de las Estrellas), and KSWB-TV 69 (Fox). San Diego has an 80.6 percent cable penetration rate.

Due to the ratio of U.S. and Mexican-licensed stations, San Diego is the largest media market in the United States that is legally unable to support a television station duopoly between two full-power stations under FCC regulations, which disallow duopolies in metropolitan areas with fewer than nine full-power television stations and require that there be eight unique station owners that remain once a duopoly is formed (there are only seven full-power stations on the California side of the San Diego-Tijuana market). Though the E. W. Scripps Company owns KGTV and KZSD-LP, they are not considered a duopoly under the FCC's legal definition as common ownership between full-power and low-power television stations in the same market is permitted regardless to the number of stations licensed to the area. As a whole, the Mexico side of the San Diego-Tijuana market has two duopolies and one triopoly (Entravision Communications owns both XHAS-TV and XHDTV-TV, Azteca owns XHJK-TV and XHTIT-TV, and Grupo Televisa owns XHUAA-TV and XEWT-TV along with being the license holder for XETV-TV, which was formerly managed by California-based subsidiary Bay City Television).

San Diego's television market is limited to only San Diego County. The Imperial Valley, including El Centro, is in the Yuma, Arizona television market while neighboring Orange and Riverside counties are part of the Los Angeles market. (Sometimes in the past, a missing network affiliate in the Imperial Valley would be available on cable TV from San Diego.) As a result, San Diego is the largest single-county media market in the United States.

The radio stations in San Diego include nationwide broadcaster iHeartMedia; Entercom Communications, Local Media San Diego, and many other smaller stations and networks. Stations include: KOGO AM 600, KGB AM 760, KCEO AM 1000, KCBQ AM 1170, K-Praise, KLSD AM 1360, KFSD 1450 AM, KPBS-FM 89.5, Channel 933, Star 94.1, FM 94/9, FM News and Talk 95.7, Q96 96.1, KyXy 96.5, Free Radio San Diego (AKA Pirate Radio San Diego) 96.9FM FRSD, KWFN 97.3, KXSN 98.1, Big-FM 100.7, 101.5 KGB-FM, KLVJ 102.1, KSON 103.7, Rock 105.3, and another Pirate Radio station at 106.9FM, as well as a number of local Spanish-language radio stations.

Transport With the automobile being the primary means of transportation for over 80 percent of residents, San Diego is served by a network of freeways and highways. This includes Interstate 5, which runs south to Tijuana and north to Los Angeles; Interstate 8, which runs east to Imperial County and the Arizona Sun Corridor; Interstate 15, which runs north-east through the Inland Empire to Las Vegas and Salt Lake City; and Interstate 805, which splits from I-5 near the Mexican border and rejoins I-5 at Sorrento Valley.

Major state highways include SR 94, which connects downtown with I-805, I-15 and East County; SR 163, which connects downtown with the north-east part of the city, intersects I-805 and merges with I-15 at Miramar; SR 52, which connects La Jolla with East County through Santee and SR 125; SR 56, which connects I-5 with I-15 through Carmel Valley and Rancho Peñasquitos; SR 75, which spans San Diego Bay as the San Diego-Coronado Bridge, and also passes through South San Diego as Palm Avenue; and SR 905, which connects I-5 and I-805 to the Otay Mesa Port of Entry.

The stretch of SR 163 that passes through Balboa Park is San Diego's oldest freeway, and has been called one of America's most beautiful parkways.

San Diego's roadway system provides an extensive network of cycle routes. Its dry and mild climate makes cycling a convenient year-round option; however, the city's hilly terrain and long average trip distances make cycling less practicable. Older and denser neighborhoods around the downtown tend to be oriented to utility cycling. This is partly because of the grid street patterns now absent in newer developments farther from the urban core, where suburban style arterial roads are much more common. As a result, the majority of cycling is recreational. In 2006, San Diego was rated the best city (with a population over 1 million) for cycling in the U.S.

San Diego is served by the San Diego Trolley light rail system, by the SDMTS bus system, private jitneys in some neighborhoods, and by Coaster and Amtrak Pacific Surfliner commuter rail; northern San Diego county is also served by the Sprinter light rail line. The trolley primarily serves downtown and surrounding urban communities, Mission Valley, east county, and coastal south bay. A mid-coast extension of the Trolley operates from Old Town to University City and the University of California, San Diego along the I-5 Freeway since November 2021. The Amtrak and Coaster trains currently run along the coastline and connect San Diego with Los Angeles, Orange County, Riverside, San Bernardino, and Ventura via Metrolink and the Pacific Surfliner. There are two Amtrak stations in San Diego, in Old Town and the Santa Fe Depot downtown. San Diego transit information about public transportation and commuting is available on the Web and by dialing "511" from any phone in the area.

The city has two major commercial airports within or near its city limits. Downtown San Diego International Airport (SAN), also known as Lindbergh Field, is the busiest single-runway airport in the world. It served over 24 million passengers in 2018, and is dealing with larger numbers every year. It is located on San Diego Bay, three miles (4.8 km) from downtown, and maintains scheduled flights to the rest of the United States (including Hawaii), as well as to Canada, Germany, Mexico, Japan, and the United Kingdom. It is operated by an independent agency, the San Diego Regional Airport Authority. Tijuana International Airport has a terminal within the city limits in the Otay Mesa district connected to the rest of the airport in Tijuana, Mexico, via the Cross Border Xpress cross-border footbridge. It is the primary airport for flights to the rest of Mexico, and offers connections via Mexico City to the rest of Latin America. In addition, the city has two general-aviation airports, Montgomery Field (MYF) and Brown Field (SDM).

Recent regional transportation projects have sought to mitigate congestion, including improvements to local freeways, expansion of San Diego Airport, and doubling the capacity of the cruise ship terminal. Freeway projects included expansion of Interstates 5 and 805 around "The Merge" where these two freeways meet, as well as expansion of Interstate 15 through North County, which includes new high-occupancy-vehicle (HOV) "managed lanes". A tollway (the southern portion of SR 125, known as the South Bay Expressway) connects SR 54 and Otay Mesa, near the Mexican border. According to an assessment in 2007, 37 percent of city streets were in acceptable condition. However, the proposed budget fell $84.6 million short of bringing streets up to an acceptable level. Expansion at the port has included a second cruise terminal on Broadway Pier, opened in 2010. Airport projects include expansion of Terminal Two.

Utilities Water is supplied to residents by the Water Department of the City of San Diego. The city receives most of its water from the Metropolitan Water District of Southern California.

Gas and electric utilities are provided by San Diego Gas & Electric, a division of Sempra Energy.

Street lights In the mid-20th century the city had mercury vapor street lamps. In 1978, the city decided to replace them with more efficient sodium vapor lamps. This triggered an outcry from astronomers at Palomar Observatory 60 miles (100 km) north of the city, concerned that the new lamps would increase light pollution and hinder astronomical observation. The city altered its lighting regulations to limit light pollution within 30 miles (50 km) of Palomar.

In 2011, the city announced plans to upgrade 80% of its street lighting to new energy-efficient lights that use induction technology, a modified form of fluorescent lamp producing a broader spectrum than sodium vapor lamps. The new system is predicted to save $2.2 million per year in energy and maintenance. The city stated the changes would "make our neighborhoods safer". They also increase light pollution.

In 2014, San Diego announced plans to become the first U.S. city to install cyber-controlled street lighting, using an "intelligent" lighting system to control 3,000 LED street lights.