Oxford House is a First Nations Cree community in northern Manitoba, located on the Oxford House 24 Indian Reserve. The community is located along the eastern shore of Oxford Lake at the mouth of Hayes River, 950 kilometres (590 mi) north of Winnipeg. The Hayes River was designated a Canadian Heritage River in 2006. The Bunibonibee Cree Nation have reserved for themselves 13 separate tracts, of which Oxford House 24 serves as their main reserve, containing the settlement of Oxford House.
Oxford House has a population of over 1,950 people.